Pronunciation: DES-i-ROO-din
Generic Name: Desirudin
Brand Name: Iprivask
Tell your doctor you use Iprivask before you have any type of spinal puncture or epidural/spinal anesthesia. Patients who have these procedures while they use Iprivask are at risk of developing a blood clot on or near the spinal cord. This could result in long-term or permanent paralysis.
The risk is increased in patients who have an indwelling epidural catheter, traumatic or repeated epidural or spinal puncture, or a history of a deformed spine or spinal surgery, and in patients who use medicines that may affect blood clotting, such as warfarin, aspirin, platelet inhibitors (eg, clopidogrel), and nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, naproxen).
If you have a spinal puncture or epidural/spinal anesthesia while you use Iprivask, tell your doctor right away if you notice any signs or symptoms of nerve problems, such as numbness or tingling, muscle weakness, or paralysis.
Iprivask is used for:
Preventing blood clots in patients having hip replacement surgery. It may also be used for other conditions as determined by your doctor.
Iprivask is a thrombin inhibitor. It works by blocking the activity of thrombin, which helps to prevent the formation of blood clots.
Do NOT use Iprivask if:
- you are allergic to any ingredient in Iprivask or to another hirudin (eg, lepirudin)
- you have active major bleeding or bleeding problems that cannot be stopped
Contact your doctor or health care provider right away if any of these apply to you.
Before using Iprivask:
Some medical conditions may interact with Iprivask. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have bleeding problems (eg, hemophilia), blood vessel problems, or an increased risk of bleeding
- if you have recently had any kind of surgery, a head injury, a stroke, a certain blood collection procedure (eg, arterial puncture), or an organ biopsy
- if you have a heart infection (eg, bacterial endocarditis), a certain adrenal gland tumor (pheochromocytoma), severe or uncontrolled high blood pressure, stomach ulcers, liver problems (eg, cirrhosis), or kidney problems
- if you have a history of bleeding in the brain, lungs, or eyes; bleeding stomach ulcers; or you have eye problems caused by diabetes (diabetic retinopathy)
Some MEDICINES MAY INTERACT with Iprivask. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin, heparin), dextran 40, dipyridamole, glucocorticoids (eg, prednisone), glycoprotein IIb/IIa inhibitors (eg, abciximab), NSAIDs (eg, ketorolac, ibuprofen), platelet aggregation inhibitors (eg, ticlopidine, clopidogrel), salicylates (eg, aspirin), sulfinpyrazone, or thrombolytics (eg, streptokinase) because the risk of bleeding problems may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Iprivask may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Iprivask:
Use Iprivask as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Iprivask is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Iprivask at home, a health care provider will teach you how to use it. Be sure you understand how to use Iprivask. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle.
- Do not mix Iprivask with other injections.
- Do not use Iprivask if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Iprivask, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Iprivask.
Important safety information:
- Lab tests, including blood pressure, kidney function, blood clotting, and complete blood cell counts, may be performed while you use Iprivask. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Iprivask with caution in the ELDERLY; they may be more sensitive to its effects.
- Use Iprivask with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if Iprivask can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Iprivask while you are pregnant. It is not known if Iprivask is found in breast milk. If you are or will be breast-feeding while you use Iprivask, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Iprivask:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Redness or discomfort at the injection site.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; black or bloody stools; confusion; dark or bloody urine; fainting; fever; increased drainage or oozing from a wound; mass at the injection site; nausea or vomiting; one-sided weakness; severe or persistent dizziness, tiredness, or weakness; slurred speech; swelling of the legs; tingling or numbness (especially in the legs and feet) and muscle weakness; unusual or severe bleeding or bruising; vision problems; vomit that looks like coffee grounds.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Iprivask side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Iprivask:
Iprivask is usually handled and stored by a health care provider. If you are using Iprivask at home, store Iprivask as directed by your pharmacist or health care provider. Keep Iprivask out of the reach of children and away from pets.
General information:
- If you have any questions about Iprivask, please talk with your doctor, pharmacist, or other health care provider.
- Iprivask is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Iprivask. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Iprivask resources
- Iprivask Side Effects (in more detail)
- Iprivask Use in Pregnancy & Breastfeeding
- Iprivask Drug Interactions
- Iprivask Support Group
- 0 Reviews for Iprivask - Add your own review/rating
- Iprivask Prescribing Information (FDA)
- Iprivask Advanced Consumer (Micromedex) - Includes Dosage Information
- Iprivask Concise Consumer Information (Cerner Multum)
- Iprivask Monograph (AHFS DI)
- Desirudin Professional Patient Advice (Wolters Kluwer)
Compare Iprivask with other medications
- Deep Vein Thrombosis, Prophylaxis
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